Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 125 entries
Sorted by: Best Match Show Resources per page
Screening of Small Molecule Microarrays for Ligands Targeted to the Extracellular Epitopes of Living Cells.

Microarrays (Basel, Switzerland)

Lee JH, Bao K, Frangioni JV, Choi HS.
PMID: 26435848
Microarrays (Basel). 2015;4(1):53-63. doi: 10.3390/microarrays4010053.

The screening of living cells using high-throughput microarrays is technically challenging. Great care must be taken in the chemical presentation of potential ligands and the number of collisions that cells make with them. To overcome these issues, we have...

Microarray Technology Applied to Human Allergic Disease.

Microarrays (Basel, Switzerland)

Hamilton RG.
PMID: 28134842
Microarrays (Basel). 2017 Jan 28;6(1). doi: 10.3390/microarrays6010003.

IgE antibodies serve as the gatekeeper for the release of mediators from sensitized (IgE positive) mast cells and basophils following a relevant allergen exposure which can lead to an immediate-type hypersensitivity (allergic) reaction. Purified recombinant and native allergens were...

A New Distribution Family for Microarray Data.

Microarrays (Basel, Switzerland)

Kelmansky DM, Ricci L.
PMID: 28208652
Microarrays (Basel). 2017 Feb 10;6(1). doi: 10.3390/microarrays6010005.

The traditional approach with microarray data has been to apply transformations that approximately normalize them, with the drawback of losing the original scale. The alternative stand point taken here is to search for models that fit the data, characterized...

Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders.

Microarrays (Basel, Switzerland)

Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP.
PMID: 26998349
Microarrays (Basel). 2016 Mar;5(1). doi: 10.3390/microarrays5010006. Epub 2016 Mar 07.

Genome-wide association studies of schizophrenia encompassing the major histocompatibility locus (MHC) were highly significant following genome-wide correction. This broad region implicates many genes including the MHC complex class II. Within this interval we examined the expression of two MHC...

Molecular Diagnostic Applications in Colorectal Cancer.

Microarrays (Basel, Switzerland)

Huth L, Jäkel J, Dahl E.
PMID: 27600342
Microarrays (Basel). 2014 Jun 26;3(3):168-79. doi: 10.3390/microarrays3030168.

Colorectal cancer, a clinically diverse disease, is a leading cause of cancer-related death worldwide. Application of novel molecular diagnostic tests, which are summarized in this article, may lead to an improved survival of colorectal cancer patients.  Distinction of these...

A New Modified Histogram Matching Normalization for Time Series Microarray Analysis.

Microarrays (Basel, Switzerland)

Astola L, Molenaar J.
PMID: 27600344
Microarrays (Basel). 2014 Jul 01;3(3):203-11. doi: 10.3390/microarrays3030203.

Microarray data is often utilized in inferring regulatory networks. Quantile normalization (QN) is a popular method to reduce array-to-array variation. We show that in the context of time series measurements QN may not be the best choice for this...

Protein Microarrays with Novel Microfluidic Methods: Current Advances.

Microarrays (Basel, Switzerland)

Dixit CK, Aguirre GR.
PMID: 27600343
Microarrays (Basel). 2014 Jul 01;3(3):180-202. doi: 10.3390/microarrays3030180.

Microfluidic-based micromosaic technology has allowed the pattering of recognition elements in restricted micrometer scale areas with high precision. This controlled patterning enabled the development of highly multiplexed arrays multiple analyte detection. This arraying technology was first introduced in the...

Particle-Based Microarrays of Oligonucleotides and Oligopeptides.

Microarrays (Basel, Switzerland)

Nesterov-Mueller A, Maerkle F, Hahn L, Foertsch T, Schillo S, Bykovskaya V, Sedlmayr M, Weber LK, Ridder B, Soehindrijo M, Muenster B, Striffler J, Bischoff FR, Breitling F, Loeffler FF.
PMID: 27600347
Microarrays (Basel). 2014 Oct 28;3(4):245-62. doi: 10.3390/microarrays3040245.

In this review, we describe different methods of microarray fabrication based on the use of micro-particles/-beads and point out future tendencies in the development of particle-based arrays. First, we consider oligonucleotide bead arrays, where each bead is a carrier...

Expression Comparison of Oil Biosynthesis Genes in Oil Palm Mesocarp Tissue Using Custom Array.

Microarrays (Basel, Switzerland)

Wong YC, Kwong QB, Lee HL, Ong CK, Mayes S, Chew FT, Appleton DR, Kulaveerasingam H.
PMID: 27600348
Microarrays (Basel). 2014 Nov 13;3(4):263-81. doi: 10.3390/microarrays3040263.

Gene expression changes that occur during mesocarp development are a major research focus in oil palm research due to the economic importance of this tissue and the relatively rapid increase in lipid content to very high levels at fruit...

t-Test at the Probe Level: An Alternative Method to Identify Statistically Significant Genes for Microarray Data.

Microarrays (Basel, Switzerland)

Boareto M, Caticha N.
PMID: 27600352
Microarrays (Basel). 2014 Dec 16;3(4):340-51. doi: 10.3390/microarrays3040340.

Microarray data analysis typically consists in identifying a list of differentially expressed genes (DEG), i.e., the genes that are differentially expressed between two experimental conditions. Variance shrinkage methods have been considered a better choice than the standard t-test for...

Overview on Techniques to Construct Tissue Arrays with Special Emphasis on Tissue Microarrays.

Microarrays (Basel, Switzerland)

Vogel U.
PMID: 27600339
Microarrays (Basel). 2014 Apr 17;3(2):103-36. doi: 10.3390/microarrays3020103.

With the advent of new histopathological staining techniques (histochemistry, immunohistochemistry, in situ hybridization) and the discovery of thousands of new genes, mRNA, and proteins by molecular biology, the need grew for a technique to compare many different cells or...

Qualitative and Quantitative Requirements for Assessing Prognostic Markers in Prostate Cancer.

Microarrays (Basel, Switzerland)

Burdelski C, Matuszewska A, Kluth M, Koop C, Grupp K, Steurer S, Wittmer C, Minner S, Tsourlakis MC, Sauter G, Schlomm T, Simon R.
PMID: 27600340
Microarrays (Basel). 2014 Apr 17;3(2):137-58. doi: 10.3390/microarrays3020137.

Molecular prognostic markers are urgently needed in order to improve therapy decisions in prostate cancer. To better understand the requirements for biomarker studies, we re-analyzed prostate cancer tissue microarray immunohistochemistry (IHC) data from 39 prognosis markers in subsets of...

Showing 1 to 12 of 125 entries